History of the building can be traced back to the end of the 16th and early 17th century, when above the western Diocletian baths, built in the 4th century, the complex of Renaissance - Baroque palace was built.

In the early 20th century the Palace was adapted to Hotel Slavija.

Renaissance stairs lead inside Hotel Slavija, which is protected by the Republic of Croatia as a national cultural heritage. Due to its location within the Diocletian's palace, Hotel Slavija is protected by the UNESCO as an international monument of culture